期刊文献+

帕利哌酮缓释片和奥氮平治疗精神分裂症的疗效和副反应的比较 被引量:1

下载PDF
导出
摘要 目的观察帕利哌酮缓释片和奥氮平治疗精神分裂症的疗效和副反应。方法将111例符合ICD-10诊断的精神分裂患者随机分成治疗组和对照组,治疗组给予帕利哌酮缓释片治疗,对照组给予奥氮平治疗,全程8周,采用PANSS量表评定疗效,用药物副反应量表评定不良反应。结果两组治疗结束时,两组显效率PANSS比较差异,无统计学意义,治疗组不良反应发生率与对照组各不相同。结论帕利哌酮缓释片和奥氮平对于精神分裂症均有显著疗效,但是不良反应各不相同。
出处 《海峡药学》 2016年第11期114-115,共2页 Strait Pharmaceutical Journal
  • 相关文献

参考文献3

二级参考文献14

  • 1Owen RT.Extended-release paliperidone:efficacy,safety and tolerability profile of a new atypical antipsychotic[J].Drugs Today(Barc),2007,43(4):249-258.
  • 2Pani L,Marchese G.Expected clinical benefits of paliperidone extended-release formulation when compared with risperidonei mmediate-release[J].ExpertOpin Drug Deliv,2009,6(3):319-331.
  • 3张鸿燕,李华芳,王刚,等.帕利哌酮缓释片治疗急性精神分裂症疗效及安全性的对照研究[J].中华精神科杂志,2011,24(6):441-443.
  • 4Karlsson P,DenckeRr D,Nyberg S,et aL.Pharmacoki-netics and dopamine d2 and serotonin T-HT2A receptor occupancy of paliperi- done subiects[J1.Eur Neuropsvcho Pharmacol,2005,15(3):385.
  • 5Moller H J. Antipsychotic agents. Gradually improving treatment from the traditional oral neuroleptics to the first atypical depot[J]. Eur Psychiat, 2005,20 (5/6) : 379-385.
  • 6Lublin H, Eberhard J, Levander SI Current therapy is- sues and unmet clinical needs in the treatment of schizo- phrenia:a review of the new generation antipsychotics [J]. Int Clin Psychopharmacol,2005,20(4) : 183-198.
  • 7Chwieduk C M,Keating G M. Paliperidonr extended re- lease=a review of its use in the management of schizo- phrenia[J]. Drugs, 2010,70 (10) : 1295-1317.
  • 8Americandiavetes Association,American Psychiatric As- sociation,American Association of CIinical Endocrinolo- gists,North American Association for the Study of obe- sity. Consensus development conference on antipsychotic drugs and obesity and diabetes[J]. Diabetes Care, 2004, 27(2) :596-601.
  • 9Americandiavetes Association,American Psychiatric As- sociation,American Association of Clinical Endocrinolo- gists, North American Association for the Study of Obe- sity. Consensus development conference on antipsychotic drugs and obesity and diabetes [J]. J Clin Psychiat, 2004,65(2) :267-272.
  • 10Schreiner A,Niehaus D,Shuriquie N A, et al. Metabolic effects of palipridone extended release verus oral olanz- pine in patients with schizophrenia[J]. J Clin Psycho Dharmacol, 2012,32(4) :449-457.

共引文献9

同被引文献9

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部