小柴胡汤加减联合认知行为干预对失眠症患者睡眠质量、结构的影响

Effect of Combination Usage of Xiaochaihu Tang and Cognitive Behavior Intervention on Sleep Quality and Structure of Patients with Insomnia

目的:观察小柴胡汤加减联合认知行为干预对失眠症患者睡眠质量、结构的影响。方法:选取90例肝经郁热型失眠症患者,随机抽签分为观察组与对照组各45例,对照组给予艾司唑仑片治疗,观察组给予小柴胡汤加减联合认知行为干预。观察治疗2周。比较2组患者的临床疗效、副反应量表(TESS)评分与治疗前后的睡眠障碍量表(SDRS)评分、匹兹堡睡眠质量(PSQI)评分。结果:观察组总有效率为84.44%,高于对照组的64.44%,差异有统计学意义(P<0.05)。治疗后,2组SDRS评分、PSQI评分均较治疗前降低,差异均有统计学意义(P<0.05),观察组SDRS评分、PSQI评分低于对照组,差异均有统计学意义(P<0.05)。观察组TESS评分低于对照组,差异有统计学意义(P<0.05)。结论:采用小柴胡汤加减联合认知行为干预治疗肝经郁热型失眠症患者,可使睡眠结构得到有效的改善,睡眠质量得到显著提高,副作用更小,比起口服艾司唑仑片更加安全有效。

Objective： To observe the effect of the com bination usage of X iaochaihu tang and cognitive behavior intervention on sleep quality and structure for patients w ith insom nia. Methods： Selected 90 patients w ith insom nia, and divided into the observation group and the control group, 45 cases in each group. The observation group w as given the therapy of Estazolam tablets. The control group w as given the therapy of com bination usage of X iaochaihu tang and cognitive behavior intervention. O bservation treatm ent for 2 w eeks. C om pared clinical effect of tw o groups, treatm ent em ergent sym ptom scale（TESS） score,Sleep D ysfunction R ating Scale（SD R S） score and Pittsburgh Sleep Q uality Index（PSQ I） score of tw o groups. Results：The total effective rate w as 84.44% in the observation group,higher than the 64.44% in the control group,the difference being significant（P〈0.05）. A fter treatm ent,SD R S scores and PSQ I scores of the tw o groups w ere decreased（P〈0.05）. SD R S scores and PSQ I scores of the observation group w ere low er than those of the control group,the differences both being significant（P〈0.05）. TESS scores of the observation group w ere low er than those of the control group（P〈0.05）. Conclusion：The com bination usage of X iaochaihu tang and cognitive behavior intervention can effectively im prove the sleep structure and quality of the patient w ith insom nia. A dverse responses are slight. Its safety and effect are m ore apparent than oral adm inistration of Estazolam tablets.