冠状动脉粥样硬化性心脏病与心脏神经症患者baPWV、IMT及中医体质相关性分析

Correlation Analysis of Coronary Atherosclerotic Cardiopathy and the ba PWV, IMT of Patients with Cardiac Neurosis with the Constitution of Traditional Chinese Medicine

目的:观察冠状动脉粥样硬化性心脏病(CAD)与心脏神经症(CN)患者的肱踝脉搏波传导速度(ba PWV)和颈动脉内膜-中膜厚度(IMT),并探讨其与中医体质的关系。方法:选择符合标准的患者40例,据诊断标准分为CAD组30例和CN组10例。测定其IMT值及ba PWV、ABI值。收集数据后应用SPSS 17.0统计软件分析。结果:1 CAD组与CN组比较:年龄、BMI、ABI差异无统计学意义(P>0.05)。CAD组的ba PWV明显比CN组增快(P<0.01),CAD组的IMT明显比CN组增厚(P<0.01)。2简单相关分析提示ba PWV与IMT呈正相关(r=0.325,P<0.05)。3 AD组中气虚体质患者最多占26.7%,其次是阴虚质占16.7%,阳虚质与气郁质各占14.3%,痰湿质和血瘀质各占10.0%;CN组以平和质为主占40.0%,其次为气虚质占30.0%,阴虚质、湿热质、气郁质各占10.0%。各证型间ba PWV及IMT的比较,差异均无统计学意义(P>0.05)。说明2组在ba PWV及IMT方面的影响无差异性。结论:ba PWV与IMT能较好地鉴别CAD与CN。中医体质与其可能有一定相关性,但限于样本量,未得出显性结论。

Objective： To obs.erve the brachial-ankle pulse wave velocity （baPWV） and cardiac neuropathy （CN） and carotid intima-media thickness （IMT） in patients with coronary atherosclerotic heart disease （CAD）, and to explore its relationship with TCM constitution. Methods： 40 patients were divided into CAD group （30 cases） and CN group （10 cases） according to the diagnostic criteria. The IMT and baPWV, ABI were measured（Data were collected and analyzed by SPSS 17.0 statistical software. Results： （1） There was no significant difference in age, BMI and ABI between CAD group and CN group （P〉0.05）. The baPWV of the CAD group was significantly higher than that of CN group （P〈0.01）. IMT of CAD group was significantly thicker than CN group （P〈0.01）. （2） Simple correlation analysis showed a positive correlation between baPWV and IMT （r = 0.325, P〈0.05）. （3）AD group had 26.7% Qi deficiency constitution, 16.7%yang deficiency constitution, 14.3% yang deficiency constitution and Qi stagnation constitution, 10.0% phlegm damp- ness and blood stasis quality respectively; Accounting for 40.0%, followed by the quality of Qi accounted for 30.0%, yin deficiency, damp heat, qi stagnation, each 10.0%. There was no statistically significant difference in baPWV and IMT between the two syndromes （P〉0.05）. Note 2 group in the haPWV and IMT no difference in the impact.Conclusion： Both baPWV and IMT can discriminate between CAD and CN. TCM constitution may have a certain correlation, but limited to the sample size, did not draw a dominant conclusion