摘要
目的以冠状动脉造影"金标准"为依据,探讨应用热断层扫描成像(TTM)技术筛查冠心病的效果。方法选择190例怀疑冠心病拟行冠状动脉造影检查的患者为研究对象,收集临床资料,完成心电图、超声心动图检查,盲法进行TTM扫描后,按照标准方法完成冠状动脉造影。结果 190例患者中,有心绞痛症状172例,心电图阳性发现88例,超声心动图阳性发现16例;冠状动脉造影显示冠心病患者130例;TTM提示心肌供血不足150例。应用TTM判断冠心病的灵敏度为100%,特异度为66.67%,正确率为89.47%。相对于临床症状、心电图和超声心动图检查三种方法来讲,TTM检查的灵敏度和正确率最高。并且,TTM可以判断心肌供血不足的程度。结论TTM作为一项完全无创的检查不仅能够灵敏地筛查出冠心病患者,还能够反映出冠心病患者的病情严重程度。
Aim Based on the result of coronary angiography,to explore the effect of thermal texture mapping(TTM) technology screening coronary heart disease(CHD). Methods 190 cases of suspected CHD patients were enrolled as the research object. The clinical data,electrocardiogram,echocardiography,TTM,and coronary angiography were finished according to standard methods. Results There were 172 cases of patients with angina symptoms,88 cases with positive electrocardiogram(ECG) findings,and 16 cases with positive echocardiography findings. Coronary angiography showed that 130 patients with CHD; while TTM showed 150 cases with inadequate myocardial blood supply.Based on the result of coronary angiography,the sensitivity and specificity of TTM to diagnose CHD was 100%,66. 67%;the accuracy was 89. 47%. Compared with the clinical symptoms,electrocardiogram and echocardiography,the sensitivity and accuracy of TTM were the highest among these four methods. Meanwhile,the severity of myocardial ischemia judged by TTM was accordant with the biggest coronary stenosis rate determined by using coronary angiography. Conclusion As a completely noninvasive examination,TTM not only has the sensitivity to detect CHD,but also can reflect the severity of coronary stenosis.
出处
《中国动脉硬化杂志》
CAS
北大核心
2016年第11期1128-1132,1137,共6页
Chinese Journal of Arteriosclerosis
基金
卫生部医药卫生科技发展研究中心专项课题(W2010T01)
关键词
热断层扫描成像
冠心病
冠状动脉造影
Thermal Texture Mapping
Coronary Heart Disease
Coronary Angiography