安钠咖滥用人群HCV感染影响因素分析

Prevalence and influencing factors of HCV infection among sodium benzoate abusers

目的调查分析武威市民勤县吸食安钠咖人群丙肝病毒(HCV)的感染现状及影响因素,为在该地区更好地开展丙型肝炎防治工作提供科学依据。方法采用多阶段系统整群抽样方法,于2011年1—3月在甘肃省武威市民勤县以招募者为调查对象,采静脉血检测HCV抗体。结果本次共调查1 021人,口吸安钠咖为89.62%(915/1 021),丙肝的感染率为2.6%。非条件logistic回归分析显示,有手术史、输过血者和丙肝密接者是感染丙肝的危险性高(P值分别为0.02、0.00和0.01)。结论本地吸食以口吸为主,丙肝感染率低。

Objective To investigate the prevalence and related factors of hepatitis C virus （HCV） infection among sodium benzoate abusers in Wuwei county of Gansu province and to provide evidences for HCV infection prevention in the area. Methods By using systematic multi-stage cluster sampling,we detected serum HCV antibody among residents with sodium benzoate abuse history recruited from Wuwei county in 2011. Results Among a total of 1 021 abusers,the proportion of smoking abuse of sodium benzoate was 89. 62% and the positive rate of serum HCV antibody was 2. 6%. The results of non-conditional logistic regression analysis showed that the participants with history of surgery and blood transfusion were more likely to be infected with HCV. Conclusion Smoking abuse is a dominant way and the preva- lence of HCV infection is relatively low among sodium benzoate abusers in Wuwei county of Gansu province.