上海市浦东新区2002—2012年白血病流行病学分析

Incidence and mortality of leukemia in Shanghai Pudong New Area,2002-2012

目的了解上海市浦东新区2002—2012年白血病发病与死亡流行状况。方法利用上海市肿瘤注册系统及生命统计死因核对报告等数据,使用统计软件分析浦东新区2002—2012年白血病的发病率、死亡率、标化率(ASR)及其变化趋势。结果上海市浦东新区2002年和2012年发病率分别为6.25/10万和7.68/10万,发病ASR分别为4.78/10万和5.46/10万;2002年和2012年死亡率分别为4.46/10万和6.54/10万,死亡ASR分别为3.20/10万和3.75/10万。发病率和死亡率均呈上升趋势,并于2011年达到最高峰(8.84/10万和6.86/10万)。此外,≥65岁组的发病率和死亡率最高(25.87/10万和22.63/10万),髓样白血病的发病率和死亡率(3.82/10万和2.54/10万)均高于其他类型白血病的发病率和死亡率(均≤1.60/10万)。结论上海市浦东新区白血病发病率及死亡率在2002—2012年间呈上升趋势,且高龄组及髓样白血病的发病率和死亡率都高于同比水平。

Objective To examine the incidence and mortality of leukemia among residents in Pudong New Area of Shanghai from 2002 to 2012. Methods The data on incidents and deaths of leukemia among residents in Pudong New Area of Shanghai from 2002 to 2012 were extracted from Shanghai Cancer Registry System and Records of Vital Statis- tics;then the incidence and mortality, as well as the age standardized rate （ASR） of leukemia were calculated and ana- lyzed. Results The annual incidence rate and ASR of leukemia incidence were 6.25/100 000 and 4. 78/100 000 in 2002 and 7.68/100 000 and 5.46/100 000 in 2012 ; the annual mortality rate and ASR of leukemia mortality were 4.46/ 100 000 and 3.20/100 000 in 2002 and 6. 54/100 000 and 3.75/100 000 in 2012. Both the incidence and mortality of leukemia demonstrated an increasing trend during the period and reached their peaks in 2011 （8.84/100 000 and 6. 86/ 100 000 ）. The highest incidence rate and mortality rate of leukemia （25.87/100 000 and 22.63/100 000 ） were observed among the residents aged over 65 years. The incidence rate and mortality rate of myeloid leukemia （ 3.82/100 000 and 2. 54/100 000） were higher than those of other types of leukemia （ all ≤ 1.60/100 000）. Conclusion The incidence and mortality of leukemia showed an uptrend among the residents in Pudong New Area of Shanghai, with higher inci- dence and mortality among elder residents and higher incidence and mortality of myeloid leukemia.