摘要
目的:研究射干清咳片对急性支气管炎患者血清Th1/Th2细胞因子的影响。方法:分析了2015年2月—6月辽宁中医药大学附属第二医院呼吸科、急诊科收治的25例患者的临床资料。采用Legend Plex多因子定量分析法(BioLegend LEGENDplexTM)分别检测25例患者给药前(A组)、给药后(B组)血清细胞因子的表达水平。结果:给药前后两组患者的IL-4、IFN-γ水平差异具有统计学意义(P<0.05)。结论:射干清咳片治疗急性支气管炎,可能与Th1/Th2细胞因子平衡有关。
Objective :To study the influence on the cytokines of Th1/Th2 in serum of the patients with acute bronchitis of Shegan Qingke Tablet. Methods: The clinical data of 25 patients, collected from February to June in 2015 of pneumology and emergency departments of Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine i was analyzed. Legend Plex multi factor quantitative analysis method was used to assay the expression level of cytokines in serum of the patients before( Group A) and after ( Group B) treatment. Results :The expression levels of IL - 4 and IFN - γof the two groups' patients showed statistical significance. Conclusion :The treatment effect on acute bronchitis of Shegan Qingke Tablet was possibly related to the balance of Th1/Th2.
出处
《辽宁中医杂志》
CAS
北大核心
2016年第11期2315-2316,共2页
Liaoning Journal of Traditional Chinese Medicine
基金
国家"十二五"重大新药创制项目(2012zx09303-017)
国家自然科学基金资助项目(81273927)
国家临床重点专科建设项目经费资助项目
国家中医药管理局临床中药学重点学科
辽宁省自然科学基金项目(2015020387)