发热伴高胆红素血症的诊疗思路

Diagnostic treatment approach to fever with hyperbilirubinemia

发热、高胆红素血症是疾病常见的临床表现,多种病因均可出现发热伴高胆红素血症。最常见的病因仍然是感染性疾病,其次为肿瘤和结缔组织疾病。间接胆红素与直接胆红素的比例可初步判断增多胆红素的来源,影像学资料有助于发现胆道梗阻性疾病和肝内外占位性病变。该文介绍成人发热伴高胆红素血症的常见病因,旨在帮助临床医生形成准确的诊断思路。

Fever with hyperbilirubinemia is a common manifestation of a variety of diseases and can result from many causes. Infection with pathogenic microbe is the most common cause of fever with hyperbilirubinemia, followed by neoplasm and connective tissue disease. The ratio of indirect bilirubin to direct bilirubin is a preliminary discriminating parameter for the source of the increased bilirubin. The radiology data is essential to finding the biliary obstructive diseases and malignancies. We introduced the common cause of fever with hyperbilirubinemia, aiming to help clinicians to form accurate diagnosis approach.