分析泮托拉唑钠与奥美拉唑治疗消化性溃疡的疗效及安全性

Efficacy and Safety of Pantoprazole Sodium and Omeprazole in the Treatment Peptic Ulcer

目的探讨泮托拉唑钠与奥美拉唑治疗消化性溃疡的疗效及安全性。方法选取我院收治的100例消化道溃疡患者,将其随机分为研究组与对照组,各50例。对照组采用奥美拉唑进行治疗,而研究组采用泮托拉唑钠进行治疗。结果研究组与对照组的总有效率分别为94.0%(47/50),84.0%(42/50),两组总有效率比较,差异具有统计学意义(P<0.05)。研究组与对照组不良反应发生率分别为8.0%、26.0%,两组的不良反应比较,差异有统计学意义(P<0.05)。结论用泮托拉唑钠治疗消化道溃疡患者的临床疗效满意,且并发症少。

Objective To explore the efficacy and safety of pantoprazole sodium and omeprazole for the treatment of patients with peptic ulcer. Methods Selected 100 cases of peptic ulcer patients of our hospital were randomly divided into research group and the control group,50 cases each. The control group treated with omeprazole,and the research group treated with pantoprazole sodium. Results The total effective rate of research group and the control group were respectively 94.0%（47/50）,84.0%（42/50）,which had significant difference（P〈0.05）. Research group and control group in incidence of adverse reactions were respectively 8.0%,26.0%,which the difference was statistically significant（P〈0.05）. Conclusion In patients with peptic ulcer by pantoprazole sodium,clinical curative effect was significantly,and has fewer complications.