不同剂量米非司酮治疗子宫肌瘤的效果观察

Research on Effects of Different Dosages of Mifepristone in Treatment of Uterine Fibroid

目的探讨不同剂量米非司酮治疗子宫肌瘤的临床效果。方法以我院于2015年3月-2016年3月收治的74例子宫肌瘤患者作为研究对象,随机分为对照组和观察组,各37例。给予对照组常规剂量（25 mg）米非司酮治疗,给予观察组小剂量（12.5 mg）米非司酮治疗,对比两种治疗方法的临床效果。结果观察组的治疗总有效率、不良反应发生率均优于对照组,两组差异有统计学意义（P〈0.05）。结论对子宫肌瘤患者实施小剂量米非司酮治疗,能够提高治疗效果。

Objective Clinical effects of different dosages of Mifepristone in treatment of uterine fibroid are to be studied. Methods Chose 74 patients with uterine fibroid who were treated in hospital from March 2015 to March 2016,separated them into control group and study group at random with 37 patients in each group. Patients in control group were given normal Mifepristone dosage（25 mg）for treatment,while other patients in study group were given small dosage Mifepristone（12.5 mg） for treatment,and then compared treatment effects between two groups. Results Patients＇ treatment efficacy and side-effect incidence in study group were much better than those in control group,and such differentials had statistic value（P〈0.05）. Conclusion Small dosage Mifepristone treatment for patients with uterine fibroid is significant to improve treatment efficacy.