儿科患者临床用药不良反应及合理用药探讨

Adverse Drug Reactions and Rational Use of Drugs in Pediatric Patients

目的分析儿科患者临床用药状况及不良反应,探讨临床合理用药的途径。方法选择我院2015年1月-2016年6月收治的300例儿科患者,回顾性分析其临床资料,统计临床用药出现的不良反应及不良反应发生的原因。结果 300例患儿有47例出现不良反应,不良反应发生率为15.67%。临床表现主要是皮肤、消化系统及神经系统症状,其中皮肤及附件所占百分比最高,占59.57%。不良反应发生的原因主要是用药剂量过大、用药不合理、药物配伍不合理及患儿的自身因素等。结论儿科临床用药不良反应的发生影响治疗效果及患儿安全,应重视儿科临床合理用药,提高用药的安全性,避免药物不良反应的发生。

Objective To analyze the clinical situation and adverse drug reactions in pediatric patients,and explore the way of rational drug use. Methods 300 cases of pediatric patients admitted in our hospital from January 2015 to June 2016 were selected,the clinical data were analyzed retrospectively,and the causes of adverse reactions and adverse reactions were analyzed. Results There were 47 cases of adverse reactions in 300 cases,the incidence of adverse reactions was 15.67%. Clinical manifestations of the skin,digestive system and nervous system symptoms,which accounted for the highest percentage of skin and accessories,accounting for 59.57% of the total. The main causes of adverse reactions were excessive dosage,irrational use of drugs,unreasonable compatibility of drugs,and their own factors. Conclusion The occurrence of adverse drug reactions in pediatric affect the treatment effect and the safety of the children,should pay attention to the pediatric clinical rational drug use,improve the safety of medication,avoid the occurrence of adverse drug reactions.