头孢曲松钠联合山莨菪碱静脉滴注治疗小儿急性胃肠炎病的疗效与安全性探讨

Study of Clinical Efficasy and Safety of Combined Administration of Ceftriaxone Sodium and Anisodamine for Children with Acute Gastroenteritis Via Intravenous Drip

目的研究探讨头孢曲松钠和山莨菪碱联合用药经静脉滴注治疗小儿急性胃肠炎的安全性和有效性。方法方便选取在该院于2014年6月—2016年4月接受治疗的110例小儿急性胃肠炎患儿作为治疗对象,根据随机数字表将其均分为两组,每组55例,在对两组患儿进行同样的常规治疗的基础上,对照组患者进行头孢曲松钠静脉滴注给药,治疗组患者在接受对照组患者给药的基础上,再额外进行山莨菪碱静脉给药,观察记录两组患者的治疗效果情况和治疗过程中症状改善情况。结果经过对实验数据进行统计分析可知,治疗组患儿的总体治疗有效率约为96.36%,对照组患儿的总体治疗有效率约为81.82%;且与对照组患者相比,观察组治疗症状情况也更优秀,上述数据间差异有统计学意义(P<0.05)。结论头孢曲松钠和山莨菪碱联合用药经静脉滴注治疗小儿急性胃肠炎具有良好的安全性,治疗效果显著,值得进行临床推广。

Objective To explore the safety and efficacy in treating children with acute gastroenteritis disease with ceftriaxone sodium and Anisodamine by intravenous drip. Methods Convenient selection 110 children with acute gastroenteritis patients chosen from June 2014 to April 2016 were randomly divided into two groups which contain 55 patients in each group and they were all under conventional treatment. The control groups were cured by ceftriaxone sodium and the treatment group ceftriaxone sodium with Anisodamine, then we should record the patients＇ therapy index in each treatment stage and the therapeutic effects. Results Through statistical analysis of experimental data, the control groups have an overall response rates of 96.36% and the treatment group 81.82%; and the treatment group have a better therapeutic status than the control group, all of the datas above have a significant differences（P〈0.05）. Conclusion The safety and efficacy in treating children with acute gastroenteritis disease with ceftriaxone sodium and Anisodamine by intravenous drip have a safety and efficacy,so it is worthy of clinical application.