80例睡眠期电持续状态临床分析

Clinical Analysis of 80 Cases with Electrical Status Eplilepticus in Sleep

目的:总结80例睡眠期电持续状态(ESES)患者的临床资料,提高对ESES的临床认识。方法:收集2013年1月至2015年12月由我院神经内科诊断为ESES的患者资料共80例,分析癫痫患者ESES的临床表现、脑电图特征、影像特征。结果:80例ESES患者行24h视频脑电图监测,可表现为多种形式的癫痫发作类型,不同的癫痫发作类型有着不同的预后,对于Landau-Kleffner综合征、伴有中央颞区棘波的儿童良性癫痫等临床发作及脑电异常呈良性经过预后较好,针对不同类型的发作可给予不同的抗癫痫药物。结论:24h视频脑电图监测对ESES的早期临床诊断具有一定的参考价值,为临床患者预后的判断起到一定的指导意义。

To improve the clinical understanding of electrical status eplilepticus in sleep （ES- ES） by summarizing the clinical data of 80 patients. Methods： We collected 80 ESES cases diag- nosed by our neurology department from January 2013 to December 2015, and analyzed the clini- cal manifestations, EEG features as well as image features of ESES of epileptics. Results. All 80 patients with ESES were performed with the 24-hour video eletroencephalography （EGG）. Epi- leptic seizure types appeared in multiple forms, and different seizure types had different progno- sis. For the clinic seizures of Landau Kleffner syndromes and benign epilepsy with centro-tempo- ral spikes （BECT）, the patients usually had a good prognosis. Different antiepileptic drugs were administered for different types of seizures. Conclusion. The 24-hour video EEG monitoring has a certain reference value for the early clinical diagnosis, which provides a certain guiding signifi- cance for the judgement of patients＇ prognosis.