甲状腺术后抗生素应用不合理情况调查

Survey Research on Irrational Application of Antibiotics after the Thyroid Surgery

目的探讨甲状腺患者手术后抗生素应用情况,为临床合理用药提供理论依据。方法对2015年2月—2016年2月在该院治疗的182例甲状腺患者抗生素应用情况进行回顾性调查,对抗生素应用目的、给药途径、联合用药及使用疗程等情况进行分析。结果 182例患者术后应用抗生素的有158例,抗生素使用率高达86.81%。其中39例治疗性应用抗生素(26.68%),119例患者预防性应用抗生素(75.32%);进行病原学检查的仅有18例(11.39%),静脉给药的患者121例(76.58%)。结论甲状腺患者术后使用抗生素的情况存在不合理现象,抗生素的过度使用极易导致致病菌产生耐药性,不利于患者恢复健康,因此采取有效地措施减少抗生素不合理应用,在临床应用中极为重要,值得在临床上推广。

Objective To study the application of antibiotics after the thyroid surgery and provide theoretical basis for clinical rational medication. Methods The application of antibiotics of 182 cases of thyroid patients treated in our hospital from February 2015 to February 2016 was retrospectively analyzed, and the application aim, administration route, combined medication and application curative effect were surveyed. Results In the 182 cases of patients, 158 cases applied antibiotics after the thyroid surgery, and the application rate of antibiotics was 86.81%, including 39 cases（26.68%） were with treatment application and 119 cases（75.32%） were with preventive application, only 18 cases（11.39%） were with etiological examination and 121 cases（76.58%） were with intravenous administration. Conclusion There was an irrational antibiotics application phenomenon existing in the patients after the thyroid surgery, the over-use of antibiotics is easy to cause production of drug resistant of pathogenic bacteria, which is not conducive to health recovery of patients, therefore, adopting effective measures to reduce the irrational application of antibiotics is vital in clinical application, which is worth clinical promotion.