伊宁市2013年135例阴性静脉吸毒人群队列研究分析

Research Analysis of 135 Negative Intravenous Drug Users Queue in Yining in 2013

目的对伊宁市2013年135例阴性静脉吸毒人群队列展开研究活动,分析吸毒人群危险因素。方法选取2013年内医院检测HIV阴性的吸毒人群队列135人,对队列内所有人每3个月随访调查高危吸毒行为以及性行为情况,并采集血样进行艾滋病、丙肝、梅毒抗体检测。结果随访调查1年,135例静脉吸毒人群中有23人失访、11人提前中止调查,仅有101人坚持随访,队列保持率为74.8%。艾滋病抗体阳性2例,HIV阳性率为2.0%,通过条件分析发现,安全套的使用、性伴侣吸毒与HIV抗体转阳有统计学意义(P<0.05);丙肝抗体阳性47例,HCV阳性率为46.5%,通过条件分析发现,吸毒与HCV抗体转阳有统计学意义(P<0.05);梅毒抗体阳性2例,RPR阳性率为2.0%,通过条件分析发现,性别与RPR抗体转阳有统计学意义(P<0.05)。结论通过伊宁市静脉吸毒人群队列调查发现,吸毒人群中的丙肝发生率较高,需要针对其危险因素进行对照干预,以遏制传染性病毒的传播速度。

Objective To carry out the research of 135 negative intravenous drug users queue in Yining in 2013 and analyze the risk factors of drug users. Methods 135 drug users detected with negative HIV in our hospital in 2013 were selected, and the high-risk drug taking behavior and sex behavior of them were surveyed by follow-up every three months, and the blood samples were collected for AIDS, Hepatitis C and Anti-TP detection. Results One-year follow-up survey showed that in the 135 cases of intravenous drug users, 23 cases lost to follow-up, 11 cases proposed to suspend investigation, only101 cases insisted on research survey, and the queue retention rate was 74.8%, AIDS antibody of 2 cases was positive and the HIV positive rate was 2.0%, the condition analysis showed that the use of condoms, drug taking of sex mate and HIV antibody becoming positive had statistical significance, P〈0.05, anti-HCV of 47 cases was positive, and the HCV positive rate was 46.5%, and the condition analysis showed that drug taking and HIV antibody becoming positive had statistical significance, P〈0.05, and the anti-TP of 2 cases was positive, and the RPR positive rate was 2.0%, and the condition analysis showed that the gender and PRP antibody becoming positive had statistical significance, P〈0.05. Conclusion The survey of intravenous drug users queue in Yining shows that the incidence rate of Hepatitis C in the drug users is high, and we need to carry out corresponding intervention for risk factors in order to prevent the spread speed of infectious viruses.