早期联合应用氯吡格雷与丁苯酞注射液治疗脑梗死临床效果分析

Early Analysis of Clopidogrel in Combination with NBP Injection in the Treatment of Cerebral Infarction Clinical Effect

目的探究早期联合应用氯吡格雷与丁苯酞注射液治疗脑梗死的临床效果。方法随机选择该院2014年7月—2016年3月间收治的脑梗死患者80例,采用数字表抽取法分组,对照组40例在常规治疗的基础上采用氯吡格雷治疗,观察组40例在对照组治疗的基础上采用丁苯酞注射液治疗,观察两组效果并进行比较。结果经治疗,观察组患者脑卒中量表评分情况明显优于对照组(P<0.05);观察组治疗总有效率为97.5%(39/40),明显高于对照组的72.5%(29/40);观察组患者日常生活活动能力评分情况明显优于对照组(P<0.05),两组比较差异有统计学意义(P<0.05)。80例患者均未出现明显的不良反应。结论早期联合应用氯吡格雷与丁苯酞注射液治疗脑梗死的临床效果良好,同时用药不会对患者产生十分明显的不良反应,因而指导我们在临床中借鉴和使用。

Objective To explore the clinical effect of early application of clopidogrel and dl-3-n-butylphthalide injection in treatment of cerebral infarction. Methods Random selection 80 cases of cerebral infarction patients in our hospital be- tween March July 2014 to 2016 were using digital table extraction group and the control group （40 cases） on the basis of conventional therapy with clopidogrel treatment, the observation group（40 cases） in the control treatment group based on the use of butylphthalide injection in the treatment of. To observe the effect of the two groups and compared. Results Two groups compared with the presence of significant difference, P 〈 0.05, the difference is statistically significant. The total ef- fective rate of the observation group was 97.5% （39/40）, significantly higher than that of the control group of 72.5% （29/40）, the results were significant difference （P〈0.05）, the difference .was statistically significant. Two groups of patients in the treatment of activities of daily living ability score of no significant difference, after treatment, to observe the patients activi- ties of daily living ability to score was significantly better than the control group, two groups compared with the presence of significant difference, P 〈 0.05, the difference is statistically significant. There were no obvious adverse reactions in 80 cases. Conclusion The clinical effect of early combined application of clopidogrel and butylphthalide injection in the treat- ment of cerebral infarction is good.