原发性高血压患者心电图改变与自主神经功能关系研究

Study the relationship between ECG changes and autonomic nervous function in patients with hypertension

目的研究原发性高血压患者心电图改变与自主神经功能的关系。方法选择在某院经诊室血压和动态血压检查确诊为原发性高血压的200例患者作为研究对象,依据常规心电图改变不同分别分为单纯型组(A组:单纯左心室高电压、ST-T改变和传导阻滞组);混合型组(B组:房室肥大伴ST-T改变和/或传导阻滞组)。选取同期在某院进行体检的100例健康人作为对照组(C组)。应用美高仪动态血压监测仪进行动态心电图检查,同时对动态心电图检查结果进行分析,比较三组患者心力减速力(DC)和心率变异性(HRV)的变化。结果 1 A组与C组相比,前者DC值、SDNN、r MSSD及p NN50指标稍降低或正常,差异有统计学意义(P<0.05);2 A组与B组相比,后者DC值、SDNN、r MSSD及p NN50指标降低或明显降低,差异有统计学意义(P<0.05)。结论高血压患者心电图改变为单纯型时DC、HRV损害轻;反之,混合型时DC、HRV损害重。

Objective Study the relationship between ECG changes and autonomic nervous function in patients with hypertension. Method 200 eases were diagnosed with true hypertension and chosen as experimental group, based on the normal electrocardiogram changes divided into simple group （A group： simple ]eft ventricular high voltage, ST-T change and conduction block group） . Mixed type （B group： Atrioventricular hypertrophy with ST -T change and/ or conduction block group ）. 100 cases healthy people were chosen as control groups （C group）. Compare the DC and HRV changes in three groups, with dynamic electrocardiogram. Result （1） Group A compared with group C, the DC, SDNN, rMSSD and pNN50 indicators is slightly lower or normal in group A, the difference was statistically significant （P 〈 0.05）. （2） Group A compared with group B, the DC, SDNN, rMSSD and pNN50 indicators is lower or significantly reduced, the difference was statistically significant （P 〈 0.05）. Conclusion The damage of DC, HRV is lighter when Hypertension patients electrocardiogram change for simple, on the other hand, the damage is heavy when mixed type.