基于两种研究结果的冠心病心力衰竭症状、证和证素分布特点的比较研究

Comparative study on distribution characteristics of symptoms, syndromes and syndrome elements of coronary heart disease with heart failure based on two kinds of research

目的:将文献研究和临床横断面流行病学调查的研究结果进行对比分析,以期能进一步探讨冠心病心力衰竭常见症状、证、证素的分布特点。方法:将上述两种方法中症状、证、证素部分的结果进行对比总结,并结合中医理论比较二者的异同。结果:共筛选出文献研究126篇,规范命名后文献研究的症状有145个,临床横断面流行病学调查的有170个,二者有115个相同,基本可涵盖冠心病心力衰竭常见症状;规范命名后文献研究证有43个,临床横断面流行病学调查有39个,二者有23个相同,最常见的证是气虚血瘀证、气阴两虚证、痰瘀互阻证、水饮内停证、痰浊证、心血瘀阻证、血瘀水停证、阳虚水泛证、心阳虚证;提取证素后文献研究的有23个,临床横断面流行病学调查的有25个,二者有17个相同,最常见的证素是气虚、血瘀、阴虚、水停、痰、阳虚;心、肾、脾、肺。结论:二种研究结果的冠心病心力衰竭症状、证候、证素反映出较好的一致性,但也存在着一定的差异性,值得进一步研究。

Objective： To comparative analyze the results of literature research and clinical cross-sectional epidemiological survey, and to further explore distribution characteristics of common symptoms, syndromes, syndrome elements of coronary heart disease（CHD） with chronic heart failure. Methods： The results of symptom, syndrome and syndrome element in the above two methods were summarized, and their similarities and differences were compared according to the theory of traditional Chinese medicine. Results： There were 145 symptoms in the literature after the name of specification, One hurdred and seventy symptoms in the clinical cross-sectional epidemiological investigation, among which 115 symptoms were the same, basically covering the common symptoms of CHD with heart failure; there were 43 syndromes in the literature after the name of specification, 39 in the clinical cross-sectional epidemiological investigation, and 23 syndromes were coincident, the most common syndromes were syndrome of blood stasis due to qi deficiency, syndrome of deficiency of both qi and yin, syndrome of intermingled phlegm and blood stasis, syndrome of internal stagnation of fluid, syndrome of phlegm-turbidity, syndrome of stagnant blockade of heart blood, syndrome of blood stasis and fluid stagnation, syndrome of water overflowing due to yang deficiency, syndrome of deficiency of heart yang; there were 23 literatures after the extraction of syndrome elements, 25 in the clinical crosssectional epidemiological survey, while 17 were coincident, the most common syndrome elements were qi deficiency, blood stasis, yin deficiency, fluid stagnation, phlegm, yang deficiency as well as heart, kidney, spleen, lung. Conclusion： Two research results of symptoms, syndromes, syndrome elements in CHD with heart failure show good consistency, but there exist some differences also, which deserve further research.