髋痹病临床治疗关键技术问题研究之临床病例前瞻性随机对照研究

Key techniques of clinical treatment for the disease of the hip: Clinical prospective randomized controlled study

目的:运用前期研究结果指导临床治疗,探讨其临床疗效。方法:按患者入院顺序,采用随机数字表法进行随机分组,分为实验组,对照组,实验组依据前期研究结果将患者分为气滞血瘀型、肝肾亏虚型、痰湿痹阻型3型,采用口服中药加中药外洗治疗,对照组采用口服塞来昔布胶囊加中药外洗治疗,治疗周期均为4周,统计各组1、3、9个月后的Harris和FPS-R评分结果。结果:分型辨证应用中药口服结合中药外洗治疗髋痹病,在治疗1个月后即可收到满意效果,该治疗效果至少可维持9个月;口服塞来昔布胶囊结合中药外洗治疗髋痹病,在治疗1个月时可达到满意疗效,此时,该治疗效果与中药口服治疗比较,差异无统计学意义,但该治疗方法在停药后病情容易出现反复。结论:依据中医证候分型指导中医药治疗髋痹病具有临床效果满意,药效持久,安全方便,值得应用推广。

Objective： To investigate the clinical effect of the clinical treatment by using the results of previous studies. Methods： According to the order of admission, patients with hip arthralgia were randomly divided into two groups by the random number table method, experimental group and control group. The patients in experimental group on the basis of previous research results were divided into qi stagnation and blood stasis type, the type of deficiency of liver and kidney, phlegm dampness and blood-accumulation stasis type and were treated by oral administration of Chinese medicine and traditional Chinese medicine washing. The control group was treated with oral celecoxib capsule and traditional Chinese medicine washing, and treatment period is 4 weeks. Harris and FPS-R score results were calculated of each group after 1 month, 3 months and 9 months. Results： Oral Chinese medicine combined with traditional Chinese medicine external washing in treating hip arthritis based on syndrome differentiation type, can get satisfactory effect in 1 month after treatment and the therapeutic effect can be maintained until at least nine months or less. Oral celecoxib capsule combined with traditional Chinese medicine washing in treating hip arthritis, also can reach satisfactory effect in 1 month of treatment, and the difference was not statistically significant, but the treatment after stopping condition is easy to appear again. Conclusion： The disease of the hip used Chinese medicine treatment according to the Chinese medicine symptom classification guidance can has satisfactory clinical effect, and the effect is lasting, safe and convenient, and it is worthy of promotion and application for the future.