新型二氢-3-芴酮的合成、结构表征以及荧光性质

Synthesis,crystal structure and fluorescent property of dihydrofluoren-3-one

在浓硫酸或者氯化铜催化下,3,4,5-三甲氧基苯甲醛与过量乙酰丙酮可生成4-乙酰基-5,6,7-三甲氧基-1,4a-二甲基-4,4a-二氢-3H-芴-3-酮。产物结构经过核磁共振(~1H NMR、^(13)C NMR、HH COSY、HSQC和HMBC)、液相色谱质谱联用(LC-MS)及元素分析结果表征,并由单晶衍射结果确证。产物具有较强荧光,在乙醇中最大激发波长为370 nm,最大发射波长为529 nm,可进一步开发为荧光探针。

4-acetyl-5,6,7-trimethoxy-1,4a-dimethyl-4,4a-dihydro-3H-fluoren-3-one was synthe-sized by treatment of 3,4,5-trimethoxybenzaldehyde and excessive actylacetone,using H2SO4 or CuCl2 as a catalyst.The structure was analyzed by 1 D NMR （^1 H NMR and ^13 C NMR）,2D NMR （H-H COSY, HSQC and HMBC ）,LC-MS and elemental analysis and confirmed by crystal structure.The product showed strong fluorescence in ethano （λex=370 nm,λem=529 nm）.