心肺功能五项联检测试板在急诊心胸相关疾病诊疗中的作用

Five Cardiac Markers in Emergency Diagnosis and Treatment with Related Disease Prognosis

目的心肺功能五项指标已经广泛应用于临床慢性心肺疾病的诊断,在临床急诊过程中也同样具有较高的诊断价值并可用于预后分析。本研究报道了Alere Triage心肺功能五项联检测试板的快速检测功能在临床急诊实践中的应用数据并进行分析。方法数据采集自2014年12月至2016年2月间我院急诊科收治的35例心胸症状异常患者。采用统计方法比较不同年龄段以及不同疾病类型患者中心肺功能五项指标的临床诊断价值以及预后变化情况。结果 70岁以上老年急诊患者在监测心肺功能五项指标时较为敏感,其中B型钠尿肽(B-type natriuretic peptide,BNP)、肌红蛋白(myoglobin)和D-二聚体(D-Dimer)这三项指标在呼吸功能及肺部、心脏功能障碍患者中敏感度较高。BNP和D-二聚体随着临床治疗过程有逐步转归的规律。结论心肺功能五项指标中的BNP、Myoglobin和D-二聚体灵敏度良好,BNP和D-二聚体对于患者病情的转归也具有一定的临床指导价值。

Objective The Five markers of cardiopulmonary function has been extensively used in the diagnosis of chronic pulmonary and coronary heart disease. It also can be applied in the process of clinical emergency.Here,we reported the data from using Alere Triage Profiler SOB panel, which was used for rapid identification of five indicators. Methods Thirty-five patients with abnormal symptoms of heart who were admitted in our hospital emergency department were collected. All patients were tested with the five markers of cardiopulmonary function before the clinical treatment. We compared the five markers with clinical diagnosis and prognosis in different age groups and different disease types. Results The patients who were older than 70 years were sensitive with the five markers of cardiopulmonary function,BNP（ B-Type Natriuretic Peptide）,Myoglobin and D-dimer had high sensitivities in the respiratory function and lung,heart dysfunction. BNP and D-dimer can be used as predictors for clinical treatment. Conclusion The five markers of cardiopulmonary function such as BNP,myoglobin and D-dimer have the good sensitivity,and BNP and D-dimer may also be used as predictors of disease outcome.