摘要
肌细胞增强因子2B(MEF2B)基因属于肌细胞增强因子2(MEF2)基因家族成员,广泛表达于人和动物的肌肉和神经组织中,在肌肉生成、神经系统发育和分化、肝脏纤维化等方面具有重要的作用,作者从MEF2B基因的结构、组织分布、生物学功能及研究进展等方面对该基因进行了综述。
Myocyte enhancer factor 2B （MEF2B） gene belongs to myocyte enhancer factor 2 （MEF2） gene family. They are all widely expressed in muscle and nerve tissues of human and animals. MEF2B plays an important role in the growth of muscle, development and differentiation of nerve system and liver fibrosis. This re- view mainly focused on the structural characteristics, tissue distribution, biological functions and research progress of MEF2B gene in human and animals.
基金
Supported by Financial Project from Ministry of Agriculture(2014-2130135)
Specia Fund for Basal Scientific Research of Central Public-interest Scientific Institutes,Beijing Institute of Animal Husbandry and Veterinary,Chinese Academy of Agricultura Sciences(2014ywf-yb-7)~~
