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联用美沙拉嗪与双歧三联活菌治疗溃疡性结肠炎的效果分析

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摘要 目的研究联用美沙拉嗪与双歧三联活菌治疗溃疡性结肠炎的效果。方法将近年来我院收治的84例溃疡性结肠炎患者随机分为治疗组和参照组,为参照组患者应用美沙拉嗪进行治疗,为治疗组患者联用美沙拉嗪与双歧三联活菌进行治疗,然后对比分析两组患者的血清丙二醛(MDA)值、血清超氧化物歧化酶(SOD)活力值、疾病活动指数(DAI)的评分、临床疗效及发生不良反应的情况。结果与参照组患者相比,治疗组患者在进行治疗后其MDA值较低,其SOD活力值较高,其DAI的评分较低,差异有统计学意义(P<0.05)。与参照组患者相比,治疗组患者治疗的总有效率较高,差异有统计学意义(P<0.05)。参照组患者不良反应的发生率高于治疗组患者,差异有统计学意义(P<0.05)。结论联用美沙拉嗪与双歧三联活菌治疗溃疡性结肠炎可取得理想的效果,而且安全性较高,此法值得在临床上推广应用。
作者 玄先利
出处 《当代医药论丛》 2016年第21期67-68,共2页
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  • 1欧阳钦,胡品津,钱家鸣,郑家驹,胡仁伟.对我国炎症性肠病诊断治疗规范的共识意见[J].胃肠病学,2007,12(8):488-495. 被引量:751
  • 2Moussata D,Goetz M,Gloeckner A,et al.Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo[J].Gut,2011,60(1):26-33.
  • 3Aizawa H,Kinouch Y,Negoro K,et al.HLA-B is the best candidate of susceptibility genes in HLA for Japanese ulcerative colitis[J].Tissue Antigens,2010,3(3):569-574.
  • 4Yoshida H,Yillmaz CE,Granger DN.Role of tumor necrosis factor-αin the extraintestinal thrombosis associated with colonic inflaramation?[J].Inflamm Bowel Dis,2011,17(11):2217-2223.
  • 5Matthes H,Krummenerl T,Giensch M,et al.Clinical trial:probiotic treatment of acute distal ulcerative colitis with rectally administered Escherichia coli Nissle 1917(Ec N)[J].BMC Complement Altern Med,2010,15(10):13.
  • 6Tursi A,Brandimarte G,Papa A,et al.Treatment of relapsing mild-to-moderate ulcerative colitis with the probiotic VSL#3 as adjunctive to a standard pharmaceutical treatment:a doubleblind,randomized,placebo-controlled study[J].Am J Gastroenterol,2010,105(10):2218-2227.
  • 7O′Flaherty S,Saulnier DM,Pot B,et al.How can probiotics and probiotics impact mucosal immunity?[J].Gut Microbes,2010,1(5):293-300.
  • 8Kashkooli SB, Rouhani M, Saibil F. Ultra-high dose of mesalamine to treat steroid-dependent ulcerative colitis[ J]. J Crohns Colitis, 2014, 8 (12) : 1745-1746.
  • 9Winter HS, Krzeski P, Heyman MB, et al. High- and Low-Dose Oral Delayed-Release Mesalamine in Children With Mild-to-Moderately Ac- tive Ulcerative Colitis [ J]. J Pediatr Gastroenterol Nutr, 2014, 59 (6) : 767-772.
  • 10Ishihara Tomoaki,Tanaka Ken-ichiro,Tasaka Yuichi,Namba Takushi,Suzuki Jun,Ishihara Tsutomu,Okamoto Susumu,Hibi Toshifumi,Takenaga Mitsuko,Igarashi Rie,Sato Keizo,Mizushima Yutaka,Mizushima Tohru.Therapeutic effect of lecithinized superoxide dismutase against colitis. The Journal of pharmacology and experimental therapeutics . 2008

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