摘要
肝源性糖尿病(HD)作为一种继发于肝细胞损伤及肝纤维化基础上的综合征,表现为显著升高的血糖、生长激素、胰岛素样生长因子、游离脂肪酸及细胞因子等。近年来,由于HD发病率的上升,越来越多的研究表明其发病机制与胰岛素抵抗和肝炎病毒对胰腺细胞的破坏等密切相关,本文将综述肝源性糖尿病的最新发病机制和诊疗进展。
Hepatogenous diabetes is regared as the secondary diabetes due to the damage of liver cells and liver fibrosis, it is characterized by the syndrome of high blood sugar, growth hormone, insulin-like growth factor, free fatty acid and cytokines. As the rising incidence of hepatogenous diabetes in recent years, more and more studies have begun to reveal its close relationship with the pathogenesis of insulin resistance and destruction of pancreatic cells due to the hepatitis. This article will review the latest incidence of the mechanisms and treatment progress of hepatogenous diabetes.
出处
《中国肝脏病杂志（电子版）》
CAS
2016年第3期21-25,共5页
Chinese Journal of Liver Diseases：Electronic Version
基金
青岛市医药科研指导计划(2014-WJZD144)
山东省青岛市医疗卫生优秀人才项目(靑卫科教函字【2015】20号)
关键词
糖尿病
肝源性
胰岛素抵抗
肝硬化
治疗
Diabetes
hepatogenous
Insulin resistance
Liver cirrhosis
Therapy
