摘要
MrkH is the first characterized c-di-GMP related transcrip- tional regulator which affects type 3 fimbrial expression in response to cellular c-di-GMP level, and thus plays an important role in the biofilm formation of Klebsiella pneu- moniae （Murphy and Clegg, 2012; Wilksch et al., 2011）. However, how MrkH recognizes c-di-GMP and the target DNA sequence remains obscure.
MrkH is the first characterized c-di-GMP related transcrip- tional regulator which affects type 3 fimbrial expression in response to cellular c-di-GMP level, and thus plays an important role in the biofilm formation of Klebsiella pneu- moniae （Murphy and Clegg, 2012; Wilksch et al., 2011）. However, how MrkH recognizes c-di-GMP and the target DNA sequence remains obscure.
