老年住院患者多重耐药铜绿假单胞菌感染的治疗与干预策略

Treatment of Infection of Multi-drug Resistant Pseudomonas Aeruginosa Clone in the Elderly Hospitalized Patients

目的：分析老年住院患者多重耐药铜绿假单胞菌感染的治疗与干预策略.方法：从我院2012年5月～ 2015年4月收治的老年多重耐药铜绿假单胞菌感染患者中随机抽选实施磷霉素、头孢哌酮疗法的40例作为试验组,实施头孢哌酮、阿米卡星疗法的40例作为对照组,统计疾病治疗后的效果.结果：试验组疾病缓解37例,占比92.5％;对照组疾病缓解30例,占75.0％,两组疾病缓解率对比有统计学意义,P＜0.05;试验组患者不良反应发生率为10.0％,医院感染率为7.5％,对照组患者不良反应发生率为27.5％,医院感染率为25.0％,两组差异有统计学意义,P＜0.05.结论：临床给予老年多重耐药铜绿假单胞菌感染患者磷霉素、头孢哌酮疗法作用显著,可提高疗效,预防不良反应、医院感染,值得借鉴.

OBJECTIVE ： To study the treatment of infection of multi - drug resistant pseudomonas aeruginosa clone in the elderly hospitalized patients. METHODS ： 80 patients with the infection of multi - drug resistant pseudomonas aeruginosa clone in our hospital from May 2012 to Forth 2015 were selected. These patients were divided into the treatment group （n =40） and the control group （n = 40）. The treatment group received shilinmeisu and Toupaopaitong therapy. The control group accepted Toupaopaitong and Armika treatment. The effect of the treatment in the two groups were compaired. RESULTS： In the treatment group remission rate was 92. 5% （n = 37） and in the control group75.0% （ n = 30）. There was statiscally difference （ P 〈 0.05 ）. In the control group the adverse reaction rate was 10. 0% and infection rate was 7.5% ; in the control group the adverse reaction rate 27.5% and infection rate 25.0%. There was statically difference （P 〈 0. 05）. CONCLUSION： Linmeisu and Toupaopaitong can treat the infection of multi - drug resistant pseudomonas aeruginosa clone effectively and prevent the adverse reaction and infection.