恶性肿瘤患者化疗后诱发口腔溃疡对心理状态的影响及预防分析

Influence and prevention analysis on malignant tumor patients' mental states after dental ulcer induced by chemotherapy

目的探讨恶性肿瘤患者化疗后诱发口腔溃疡对其心理状态的影响及预防措施。方法选取2013年2月至2015年1月收治的恶性肿瘤患者96例,根据化疗后是否诱发口腔溃疡分为观察组和对照组各48例,根据情况给予药物(复合维生素、康复新液等)、生理及心理干预,干预结束采用心理测评量表(SCL-90)、正性负性量表(PANAS)分析其心理及情绪状态,应用简明健康状况调查问卷(SF-36)、疼痛数字评分法(NRS)分析干预前后两组生活质量及疼痛度,并观察不良反应。结果干预前观察组SCL-90评分(253.78±5.64)分、PANAS负性情绪评分(46.32±1.11)分、NRS评分(8.31±0.55)分,高于对照组(P<0.05),观察组PANAS正性情绪评分(15.97±1.32)分、SF-36评分(90.43±1.83)分低于对照组(P<0.05),干预后两组SCL-90、PANAS正负性情绪、SF-36、NRS评分比较无显著差异(P>0.05)。结论恶性肿瘤患者化疗后诱发口腔溃疡明显影响其心理与情绪状态,采用复合维生素、生理及心理干预可改善心理、情绪、生活质量及疼痛度,值得在临床推广。

Objective To discuss the influence and prevention analysis on malignant tumor patients＇ mental states after dental ulcer induced by chemotherapy. Methods Totally 96 cases of malignant tumor patients treated in our hospital during February 2013 to January 2015 were selected as the study objectives. According to the facts that if they had dental ulcer induced by chemotherapy, the patients were divided into observation group and contrast group with each group 48 cases. Based on the patients＇ real condition, they were given medication （like decavitamin, kangfuxin solution and so on） and physical and mental intervention. After intervention, the patients were given analysis of mental and emotional states by adopting SCL - 90 and PANAS. Meanwhile, the patients＇ living quality and pain degree of before and after in- tervention were analyzed by using SF -36 and NRS. Observed the adverse reactions. Results Before intervention in the observation group, the SCL- 90 （253.78 ±5.64）scores, PANAS negative emotion（46. 32 ± 1. 11 ）scores and NRS （ 8.31±0. 55） scores were all higher than those the contrast group （ P 〈 0. 05 ）. In the observation group, the PANAS positive emotion （ 15.97 ± 1.32） scores and SF - 36 （90. 43 ± 1.83 ） scores were lower than the contrast group （ P 〈 0.05）. After intervention, the comparison of both groups＇ SCL -90, PANAS positive emotion, SF -36 and NRS showed no significant difference （ P 〉 0. 05 ）. Conclusion The dental ulcer induced by chemotherapy can obviously influence the malignant tumor patients＇ mental and emotional states. Adopting decavitamin medication, physical and mental intervention can improve the patients＇ mental and emotional states, living quality and pain degree. Thus, it de- serves to be widely promoted in the clinical field.