黄芩等6种中药对60株泛耐药鲍曼不动杆菌的抑菌效果检测

Detection of antibacterial effects by 6 kinds of traditional Chinese medicine as Scutellaria baicalensis for 60 Acinetobacter baumannii strains

目的检测黄苓、金银花、黄连、连翘、五味子以及乌梅6种中药对于60株泛耐药鲍曼不动杆菌的抑菌效果。方法 60株泛耐药鲍曼不动杆菌,采用中药抗菌实验试管倍比稀释法检测黄苓、金银花、黄连、连翘、五味子以及乌梅6种中药对泛耐药鲍曼不动杆菌的最低抑菌浓度,并对6种中药的抑菌效果加以比较。结果黄苓、金银花、黄连、连翘、五味子以及乌梅6种中药对于60株泛耐药鲍曼不动杆菌的抑制效果不同,最低抑菌浓度分别为46.22、103.13、56.01、234.47、63.54、58.85 mg/ml,不同中药对于泛耐药鲍曼不动杆菌的抑菌效果存在差异,其中黄苓的抑菌效果最好。结论黄苓、金银花、黄连、连翘、五味子以及乌梅6种中药对于60株泛耐药鲍曼不动杆菌均有抑制效果,抑制程度存在差异,其中黄苓抑菌效果最好。

Objective To detect antibacterial effects by Scutellaria baicalensis, Lonicera japonica, Coptis chinensis, Forsythia suspense, Schisandra chinensis and Fructus mume for 60 Acinetobacter baumannii strains. Methods There were 60 Acinetobacter baumannii strains taken in traditional Chinese medicine antibacterial test tubes by doubling dilution to detect minimal inhibitory concentration by Scutellaria baicalensis, Lonicera japonica, Coptis chinensis, Forsythia suspense, Schisandra chinensis and Fructus mume. Antibacterial effects by the six medicines were compared. Results Scutellaria baicalensis, Lonicera japonica, Coptis chinensis, Forsythia suspense, Schisandra chinensis and Fructus mume showed different inhibitory effects for 60 Acinetobacter baumannii strains, and their minimal inhibitory concentrations were respectively 46.22, 103.13, 56.01, 234.47, 63.54, 58.85 mg/ml. Different traditional Chinese medicines showed various antibacterial effects for Acinetobacter baumannii, while Scutellaria baicalensis provided the best effect. Conclusion All of Scutellaria baicalensis, Lonicera japonica, Coptis chinensis, Forsythia suspense, Schisandra chinensis and Fructus mume show their inhibitory effects for 60 Acinetobacter baumannii strains. With their differences in inhibitory effects, Scutellaria baicalensis contains the best antibacterial effect.