硝普钠抢救高血压并急性左心衰竭临床效果观察

Observation of clinical effect by sodium nitroprusside for rescuing hypertension complicated with acute left ventricular failure

目的探讨硝普钠抢救高血压并急性左心衰竭的临床效果。方法 60例高血压并急性左心衰竭患者,根据治疗方法不同将患者分为对照组和观察组,各30例。对照组采用硝酸甘油抢救治疗;观察组采用硝普钠抢救治疗,比较两组患者的疗效。结果观察组患者临床总有效率为93.33%,明显高于对照组的76.67%,差异具有统计学意义(P<0.05)。观察组不良反应发生率为6.67%,与对照组的10.00%比较,差异无统计学意义(P>0.05)。结论硝普钠抢救高血压并急性左心衰竭临床效果确切,安全性高,值得推广应用。

Objective To investigate clinical effect by sodium nitroprusside for rescuing hypertension complicated with acute left ventricular failure. Methods A total of 60 hypertension complicated with acute left ventricular failure patients were divided by different treatment measures into control group and observation group, with 30 cases in each group. The control group received nitroglycerin for rescue, and the observation group received sodium nitroprusside instead. Curative effects were compared between the two groups. Results The observation group had total clinical effective rate as 93.33%, which was obviously higher than 76.67% in the control group, and the difference had statistical significance（P〈0.05）. The observation group had incidence of adverse reactions as 6.67%, and the control group had that as 10.00%. Their difference had no statistical significance（P〉0.05）. Conclusion Sodium nitroprusside shows precise clinical effect in rescuing hypertension complicated with acute left ventricular failure, along with high safety. It is worth promoting and applying.