地特胰岛素在老年糖尿病人群中的应用

The Application of Insulin Detemir in Elderly Diabetic Patients

老年糖尿病患者具有患病率高、低血糖发生风险高、合并症及并发症多等临床特点,因此,在起始胰岛素治疗时应选用作用时间长、吸收平稳、变异性小、低血糖风险低的胰岛素。地特胰岛素为长效胰岛素类似物,在有效控制血糖的同时具有良好的安全性,具有减少体重增加的优势,适用于老年糖尿病人群。

Nowadays, the prevalence of type 2 diabetes in elderly people is getting high. Elderly diabetic patients are usually with higher risk of hypoglycemia and mortality. Besides, diabetes mellitus complications and comorbidities are more frequent inold diabetics than the young ones. Therefore, an optimal insulin should be used to initiate the insulin therapy. In general, long acting duration, stable absorption and small variability should be under consideration, Insulin detemir is a basal long-acting insulin analogue,it can control the hyperglycemia effectively and safely in elderly patients with type 2 diabetes mellitus. Moreover, detemir can reduce the weightgain effect of insulins.