中西医结合治疗儿童复发性口腔溃疡的临床效果分析

The clinical effect of integrating therapy of Chinese and Western medicine in children with recurrent oral ulcer

目的:评价中西医结合治疗小儿复发性口腔溃疡的临床效果及对患儿免疫功能的影响。方法:76例复发性口腔溃疡的小儿患者,随机分为实验组和对照组各38例。对照组给予西药对症支持治疗,实验组患儿在此基础上联合中药方剂调理。观察两组的溃疡愈合时间,疼痛评分,治疗有效情况及对患儿免疫功能的改善情况与治疗期间的不良反应。结果:实验组治疗后的平均愈合时间明显短于对照组(t=6.7145,P=0.0000);两组的T细胞亚群含量比较,治疗后均有所改善(P<0.05),而实验组的CD4、CD8和CD4/CD8的改善情况明显优于对照组(P<0.05);两组患者治疗期间均未发生明显不良反应。结论:采用中西医结合治疗小儿复发性口腔溃疡临床疗效显著,同时可提高患儿的免疫功能。

Objective： To evaluate the clinical effect of integrating therapy of Chinese and Western medicine in children with recurrent oral ulcer and its effect to immune function of children. Methods： Seventy-six children with recurrent oral ulcer were divided into two groups with each of 38 randomly. Adopting western medicine and supportive treatment targeting to symptom in control group and add with traditional Chinese medicine based on the treatment of control group in experimental group. Children were observed the pain score of ulcer,effectiveness of treatment,improvement of immune function and untoward reaction. Results： The healing time of the experimental group was significantly shorter than the control group after treatment（ t = 6. 7145,P = 0. 0000）. T cell subsets of content in two both groups were improved after treatment（ P 0. 05）,and the improvement of CD4,CD8 and CD4 / CD8 in experimental group had better effect than the control group（ P 0. 05）.There were no obvious untoward reactions occurred during the treatment in both two groups. Conclusion： Integrating therapy of Chinese and Western medicine in children with recurrent oral ulcers significantly,can quickly relieve the pain coursed by ulcer,while improving the immune function of children.