梧州市1999—2013年HIV感染者和AIDS病人死亡情况分析

Analysis of death of HIV-infected people and AIDS patients in Wuzhou City, 1999-2013

目的分析梧州市艾滋病病毒(HIV)感染者和艾滋病(AIDS)病人(简称HIV/AIDS)死亡情况。方法从"艾滋病综合防治信息系统"收集2013年12月31日前现住址为梧州市的HIV/AIDS死亡病例资料进行分析。结果截至2013年12月31日,梧州市累计报告1 132例HIV/AIDS死亡病例,累计病死率为29.83%(1 132/3 795);其中已参加抗病毒治疗187例(16.52%),未参加过治疗945例(83.48%);死亡病例确认阳性后1年内死亡的占47.00%(532/1 132);历年死亡病例的CD4+T淋巴细胞检测率呈逐年上升趋势(P<0.001),死亡前最近一次CD4+T淋巴细胞≤200个/μL占69.14%(392/567)。结论晚发现现象严重是导致HIV/AIDS病死率较高的主要原因,做到早发现,早治疗,进一步扩大抗病毒治疗覆盖率,才能有效降低本市的HIV/AIDS病死率。

Objective To analyze the death of human immunodeficiency virus（HIV）- infected people and acquiredimmune deficiency syndrome（AIDS） patients（HIV/AIDS cases） in Wuzhou City. Methods The personal data of HIV/AIDSpeople, who were residents in Wuzhou City and died before December 31, 2013, were downloaded from＂China NationalInformation System for HIV/AIDS Control and Prevention＂and analyzed statistically. Results Up to December 31, 2013, thetotal reported death cases amounted to 1 132, and the accumulative case fatality rate was 29.83%（1 132/3 795）. Among thesecases, 187（16.52%） received HAART, 945（83.48%） persons did not receive highly active anti-retroviral therapy（HAART）,and 532（47.00%） died in one year after confirmed HIV positive. The detection rate of CD4^＋T cell showed an increasing trendyear by year（P〈0.001）. Of these deaths, 392（69.14%） persons had CD4^＋counts lower than 200 cells/μL before death.Conclusion The leading cause of high case fatality rate is the late discovery, in order to reduce the case fatality rate of HIV/AIDS, the hard efforts should be made to achieve early detection and receive HAART early, and expand coverage of HAART.