急性缺血性卒中静脉溶栓治疗院前和院内延误现状分析

Situation Analysis of Time Delay of Pre-hospital and In-hospital of Intravenous Thrombolysis in Patients with Acute Ischemic Stroke

急性缺血性卒中(acute ischemic stroke,AIS)首选重组组织型纤溶酶原激活剂(recombinant tissue plasminogen activator,rt-PA)治疗,由于静脉溶栓有时间限制,有研究表明院前及院内时间延误是阻碍AIS患者发病后接受静脉溶栓治疗的主要因素,本文旨在探讨静脉溶栓治疗的院前和院内延误的现状、影响因素,缩短延误的改进建议,从而规范溶栓治疗体系,改进溶栓服务质量。

Recombinant tissue plasminogen activator （rt-PA） with alteplase is the ifrst choice to treat acute ischemic stroke （AIS） patients. There is a time limit for intravenous thrombolysis （IVT）. Related studies showed that pre-hospital and in-hospital time delay was a major obstacle for AIS patients to receive intravenous thrombolytic therapy. This paper aimed to explore the current situation and inlfuence factors of pre-hospital and in-hospital delay in the treatment of IVT, improvements to reduce the delay time, so as to establish standardized thrombolysis system and enhance service quality.