Ccr、CysC、Scr及BUN指标检测对肾功能不全诊断的价值分析

Value Analysis of Ccr, CysC, Scr and BUN Indexes in the Diagnosis of Renal Dysfunction

目的探究肌酐清除率(Ccr)、血清胱抑素C(CysC)、血清肌酐(Scr)及血尿素氮(BUN)指标检测对肾功能不全诊断的价值。方法选取我院接受治疗的90例肾功能不全患者为观察组,同期选取80例健康体检者为对照组,采用全自动生化仪对两组患者的血清Ccr、CysC、Scr、BUN水平进行检测,观察两组患者的上述指标以及不同分期的各项指标情况。结果观察组患者的Ccr、CysC、Scr与BUN水平高于对照组,而且不同分期时的上述指标和对照组比较,差异有统计学意义(P<0.05)。结论肾功能不全患者检测Ccr、CysC、Scr与BUN水平具有较大的意义,上述指标可视为肾功能损伤的判定指标,对该病的治疗具有较为突出的临床价值。

Objective Study on creatinine clearance（Ccr）, serum cystatin C（CysC）, serum creatinine（Scr） and blood urea nitrogen（BUN） value indexes for renal insufficiency diagnosis. Methods 90 cases of renal insufficiency patients were chosen as the observation group in our hospital, 80 healthy subjects were selected as control group, using automatic biochemical analyzer and serum in two groups of patients with Ccr, CysC, Scr and BUN levels were detected, the observation index of the two groups of patients and various indexes of different period. Results The levels of Ccr, CysC, Scr and BUN in the observation group were significantly higher than those in the control group, and there were significant differences between the two groups at different stages（P〈0.05）. Conclusion The levels of Ccr, CysC, Scr and BUN in patients with renal insufficiency are of great significance. The above indexes can be regarded as the index of renal function injury, and it is of great clinical value in the treatment of this disease.