埃索美拉唑镁针剂联合生长抑素治疗上消化道出血的应用研究

The Study of Application of Esomeprazole Magnesium Enteric-coated and Somatostatin Treatmenton Upper Gastrointestinal Bleeding

目的研究埃索美拉唑镁针剂联合生长抑素治疗上消化道出血的应用。方法选择2015年8月~2016年7月我院收治上消化道出血患者102例,随机分为常规控制组和联合止血组,联合止血组在常规控制组治疗上加用埃索美拉唑镁。结果联合止血组的呕血次数和黑便次数少于常规控制组,两组间比较差异有统计学意义（P〈0.05）。联合止血组的止血成功率为100.00%,高于常规控制组的止血成功率92.00%,两组间比较,差异有统计学意义（P〈0.05）。结论埃索美拉唑镁针剂联合生长抑素治疗上消化道出血具有较好的临床疗效,止血成功率较高且具有较好临床应用安全性,为临床治疗上消化道出血提供依据。

Objective To study the growth of esomeprazole magnesium enteric-coatedcombined with somatostatin treatment of upper digestive tract hemorrhage application. Methods From August 2015 to July 2016 in our hospital, 102 cases of patients with upper gastrointestinal bleeding, were randomly divided into normal control group and combined treatment group. The combined hemostatic group in the conventional control group treated with esomeprazole magnesium enteric-coated. Results The hemostatic group and the number of times of hematemesis melena was significantly less than the conventional control group, compared the differences between the two groups（P〈0.05）. The success rate of hemostasis in combined hemostasis group was 100.00%, which was significantly higher than that of conventional control group 92.00%, and there was a significant difference between the two groups（P〈0.05）. Conclusion Esomeprazolecombined with growth has better clinical efficacy in the treatment of upper digestive tract hemorrhage of somatostatin, hemostatic success rate is high and has good clinical safety, provide the basis for clinical treatment of upper digestive tract hemorrhage.