抗血小板药物在冠心病治疗中的疗效观察

The Effect of Antiplatelet Drug in the Treatment of Coronary Heart Disease

目的探讨分析抗血小板药物在冠心病治疗中的效果。方法本研究选取2013年3月~2016年3月我院收治的120例冠心病患者作为研究对象,随机分为观察组和对照组,各60例;对照组给予阿司匹林治疗,观察组给予氯吡格雷治疗,两组患者均连续服药26 d,对两组患者治疗前后MPA、PRI和治疗过程中不良反应发生情况进行对比分析。结果与治疗前相比,两组患者经过治疗后MPA和PRI均得到显著改善（P均〈0.01）且观察组改善程度优于对照组（P均〈0.01）;在治疗过程中,对照组不良反应发生率为11.7%（7/60）;观察组不良反应发生率为3.3%（2/60）;两组不良反应发生率比较差异无统计学意义（P〉0.05）。结论抗血小板药物用于冠心病患者的治疗可显著改善患者MPA和PRI情况,且不会增加患者不良反应的发生。

Objective To explore the clinical effect of antiplatelet drug in the treatment of coronary heart disease. Methods 120 cases of coronary heart disease were selected from March 2013 to March 2016 in our hospital, and divided into observation group and control group, 60 cases in each group. The cases in observation group were taken clopidogrel hydrogen sulfate tablets and control group was taken aspirin. All the cases were required a continuous dose for 26 days. The MPA, PRI and complications of the two groups before and after treatment were compared. Results After treatment, MPA and PRI was improved significantly as compared with thatbefore treatment（P〈0.01） and the improving degrees in observation group was better than control（P〈0.01）. The incidence of adverse reactions in control was 11.7%（7/60） and observation group 3.3%（2/60）. There was no significant difference of incidence of adverse reactions between the two groups（P〉0.05）. Conclusion Antiplatelet drug in the treatment of coronary heart disease can improve the MPA and PRI condition without complication.