某三甲医院抗菌药物专项整治前中后期使用情况调查与分析

In the use of the investigation and analysis of antibacterial drugs in a hospital before special rectification

目的:评价抗菌药物专项整治活动对某三甲医院抗菌药物应用的影响。方法:收集某院在专项整治前(2010年)、中(2012年)、后(2014年)抗菌药物使用的数据,并进行统计分析。结果:整治后,门诊、住院患者抗菌药物使用率和住院患者使用强度分别由20.19%、73.51%、93.58DDD降至13.49%、51.37%、40.34DDD;围手术期预防性使用抗菌药物的使用率、用药时机及用药时间符合率均明显改善;微生物送检率提高。抗菌药物使用量和销售金额在整治前中后排名前10位品种均集中在β内酰胺类。结论:专项整治活动显著提高了抗菌药物临床应用的合理性,但仍未完全达到要求,需加大力度整治。

Objective： To evaluate the impacts of special rectification activities on antimicrobial drug use in a hospital. Methods： The data of antibiotics clinical application before, during and after carrying out special rectification activities were collected and analyzed. Results： After carrying out special rectification activities, the utilization rates of antibiotics of outpatients and hospitalized patients decreased respectively from 20.19% and 73.51% to 13.49% and 51.37%; the use density decreased from 93.58DDD to 40.34DDD. The preventive utilization rate of antibiotics, medication timing and course accordance were significantly improved. The submission rate of microorganism was elevated. The top 10 of usage and sales amount focused on β-lactam antibiotics before, during, and after carrying out special rectification activities. Conclusion：The special rectification activities significantly improved the rationality of clinical application of antibiotics which remains not completely meeting the standard of the ministry of health so that it is necessary to further rectify.