乌司他丁与奥曲肽联合治疗轻症急性胰腺炎的临床疗效

Clinically Curative Effect of Ulinastatin Combined With Octreotide in Treatment of Patients With Mild Acute Pancreatitis

目的 探讨乌司他丁与奥曲肽联合治疗轻症急性胰腺炎的临床疗效。方法 选取我院2015年9月-2016年3月收治的22例轻症急性胰腺炎患者作为研究对象,将其随机分为对照组（11例）和观察组（11例）。两组患者均给予禁食、胃肠减压、补液、止痛、抑制胃酸分泌和抗生素治疗。对照组在此基础上加用醋酸奥曲肽,观察组在对照组基础上加用乌司他丁,观察两组患者治疗5 d后疗效。结果 对照组患者治疗总有效率为63.63%,观察组为81.81%,比较两组数据,差异有统计学意义（P〈0.05）。结论 联合应用乌司他丁和奥曲肽治疗轻症急性胰腺炎能够明显提高治疗疗效。

Objective To investigate the clinical efficacy of ulinastatin combined with octreotide in the treatment of mild acute pancreatitis. Methods22 cases of patients with mild acute pancreatitis admitted from September 2015 to March 2016 were randomly divided into the control group （11 cases） and the observation group （11 cases）. Two groups of patients were given fasting, gastrointestinal decompression, lfuid infusion, pain, inhibition of gastric acid secretion and antibiotic therapy. The control group, based on the use of octreotide acetate, the observation group in the control group based on the use of ulinastatin, to observe two groups of patients after 5 days of treatment.Results The total effective rate of the observation group was 81.81%, the total effective rate of the control group was 63.63%, the difference between two groups was statistically signiifcant （P 〈 0.05）.ConclusionThe combination of ulinastatin and octreotide in treatment of severe acute pancreatitis can significantly improve the treatment effect.