牛呼吸道感染细菌病原的致病机理与防控研究进展

Research on pathogenic mechanism and prevention of bovine respiratory tract bacterial infection

牛呼吸道疾病综合征(BRDC)是一种急性呼吸道疾病,其主要细菌性病原有多杀性巴氏杆菌、溶血性曼氏杆菌、化脓隐秘杆菌和昏睡嗜血杆菌,常见于断奶、运输等应激后牛群。该病呈世界性分布,可经呼吸道感染,严重影响肉牛及泌乳牛的品质,给养牛业造成巨大的经济损失。国内关于BRDC的研究仍比较匮乏,且尚无可预防BRDC细菌性病原的疫苗,为更好地防控BRDC,现就国内外BRDC细菌性病原的致病机理和防控研究进展做一综述。

BRDC （bovine respiratory disease complex） is one kind of acute respiratory disease in cattle,which would happen after stresses such as post-weaning or transportation. The most com- mon bacteria causing the BRDC are P. multocida ,M. haernol ytica ,A. pyogenes and H. somni. The BRDC which is widely distributed worldwide, could be transmitted by respiratory tract. The BRDC leads to worse quality of beef and dairy cattle and huge economic losses in the cattle industry. Research on the BRDC is still relatively poor in domestic,and there is no vaccine for preventing it. In order to preventing and controling BRDC, the etiology and prevention of the bacterial pathogens related to BRDC are reviewed.