摘要
空间流行病学和分子流行病学方法在结核病研究中已广泛使用，但二者均具有各自的局限性，而二者的结合则为结核病研究提供了新的思路和方法。文中所有引用文章均来自中国知网、万方数据知识服务平台、PubMed和Web of Science四个数据库。空间流行病学和分子流行病结合的方法在国外的结核病研究中已广泛使用，在确定区域地方性的流行菌株基因型、结核病传播方式及危险因素分析、耐药结核病、结核病防控措施等方面均具有重要意义，值得国内该领域的研究学者和疾病防控工作者进行借鉴和学习。
Spatial epidemiology and molecular epidemiology have been widely used in the studies of tuberculosis （TB）, but each with limitations. Integration of the two methods provides new ideas and methods in TB research. All referenced articles are from CNKI, Wan Fang database, PubMed database and Web of Science database. Method of combining spatial epidemiology and molecular epidemiology has been widely used in determining the local epidemic strains of TB genotype, the transmission mechanism, risk factors of TB, drug-resistant TB, as well as evaluating the effectiveness of TB prevention and control measures. Application of the combined methods is of important significance in the studies of TB, thus worthy to be further introduced to researchers and disease prevention and control workers in this country.
作者
陈文明
周庆荣
王晓萌
毛辉曙
王萍
周琳
王伟炳
Chen Wenming Zhou Qingrong Wang Xiaomeng Mao Huishu Wang Ping Zhou Lin Wang Weibing(Department of Epidemiology, School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Shanghai 200032, China Center for Disease Control and Prevention of Jiangshan, Jiangshan 324100, China Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2016年第12期1683-1686,共4页
Chinese Journal of Epidemiology
基金
英国国际发展部资助的中英全球卫生支持项目（GHSP.CS.OP302）
国家自然科学基金（81673233）
浙江省科技厅重大专项计划项目（2014C03034）
关键词
结核病
空间流行病学
分子流行病学
Tuberculosis
Spatial epidemiology
Molecular epidemiology
