基因工程中的风险:以人类生殖细胞系基因编辑为例（英文）

Risks in Genetic Engineering: the Case of Human Germline Gene Editing

近年来,CRISPR/Cas9系统介导的基因编辑以及其他相关技术的研究受到广泛的关注。文章讨论人类生殖细胞基因编辑的风险、社会和伦理内涵,凸显相关的风险管理问题,并反对在涉及到人类生殖细胞干预进行过早的实验。论文认为应该容纳更广泛公众讨论,并以预防原则为基础推进研究。

Recently, studies using CRISPR/Cas9-mediated gene editing and similar techniques have attracted considerable attention. This article discusses the risks and societal and ethical implications of human germline gene editing, highlights problems related to risk management and argues against the premature running of experiments involving human germline interventions. Instead, it advocates an approach based on the precautionary principle that involves a broad public debate.