胺碘酮治疗急性心肌梗死后室性心律失常的效果分析

Analysis of effect of amiodarone on ventricular arrhythmias after acute myocardial infarction

目的研究胺碘酮对急性心肌梗死后室性心律失常患者的治疗效果。方法将我院收治的182例急性心肌梗死后室性心律失常患者随机分为对照组和试验组,各91例。对照组患者采用利多卡因治疗,试验组患者采用胺碘酮治疗,观察两组患者的治疗效果,并统计两组患者的不良反应发生情况、心脏不良事件及平均复律时间。结果治疗后,试验组患者不良反应发生率及心脏不良事件发生情况显著低于对照组,平均复律时间也显著短于对照组,差异具有统计学意义(P<0.05)。试验组患者治疗有效率显著高于对照组患者,差异具有统计学意义(P<0.05)。结论胺碘酮较利多卡因对于急性心肌梗死后室性心律失常患者具有更好的治疗效果,可以有效降低患者的不良反应。

Objective To study the effect of amiodarone on ventricular arrhythmias after acute myocardial infarction. Methods One hundred and eighty-two cases of patients with ventrieular arrhythmias after acute myocardial infarction in our hospital were selected and randomly divided into control group and experiment roup, with 91 cases in each group. The control group was treated with lidocaine, while ptients in the experiment group were treated with amiodarone. The therapeutic effect of the two groups was observed, and adverse events, adverse cardiac events and mean cardioversion time were recorded. Results After the treatment, the incidence of adverse events and adverse cardiac events in the experiment group were significantly lower than those in the control group, as well as mean cardioversion time, the difference was statistically significant （P〈0.05）. The effective rate of the experiment group was significantly higher than that of the control group, the difference was statistically significant （P〈0.05）. Conclusion Compared with lidoeaine, amiodarone has better therapeutic effect for patients with ventrieular arrhythmias after acute myocardial infarction, which can effectively reduce the patients＂ adverse reactions.