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羟考酮用于模拟胸部创伤早期镇痛的效果观察

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摘要 目的:比较羟考酮与地佐辛用于模拟胸部创伤早期镇痛的临床效果。方法选择60例择期在全身麻醉下行腔镜下肺叶切除术的患者,随机分为羟考酮(Q )组和地佐辛(D )组,术后待患者出现疼痛(V A S≥5分)时,按分组予以静脉注射各种药物,比较各组患者不同时点的静息VAS评分、Ramsay镇静评分、按压自控静脉镇痛(PCIA)次数和用药后的不良反应。结果在给药后2、4、6 h D组静息VAS评分均高于Q组,差异有统计学意义(P<0.05);D组在给药后2 h和4 h的Ramsay镇静评分高于Q组,差异有统计学意义(P<0.05);在给药后2~4 h D组PCIA按压次数高于Q组,差异有统计学意义(P<0.05);2 h内出现头晕的人数高于Q组,差异有统计学意义(P<0.05)。结论胸部创伤早期镇痛中单次静脉注射羟考酮的镇痛效果要优于地佐辛,且不良反应少,值得临床推广应用。
出处 《检验医学与临床》 CAS 2016年第23期3401-3403,共3页 Laboratory Medicine and Clinic
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