良性阵发性位置性眩晕患者的骨密度研究与分析

Analysis of BPPV in patients with bone mineral density results

目的:分析良性阵发性位置性眩晕(BPPV)患者的超声骨密度结果,探讨BPPV与骨密度的关系。方法:实验组为在北京市仁和医院耳鼻咽喉科就诊并符合纳入标准的BPPV患者88例,对照组选择年龄、性别匹配且在1年内无眩晕主诉的健康志愿者76例。2组均进行专科检查、眼震视图检查、位置性试验、超声骨密度检查,根据性别、年龄、听力情况分组。结果:1实验组骨密度T值(-2.010±1.658)明显低于对照组(0.3605±0.875),差异有统计学意义(P<0.01)。2实验组骨量减少35例(39.77%)、骨质疏松26例(29.55%)、骨密度下降61例(69.32%),分别高于对照组的骨量减少13例(17.10%)、骨质疏松6例(7.89%)、骨密度下降19例(25.00%),2组比较差异有统计学意义(P<0.01)。3依年龄分层分组,实验组所有年龄层患者的骨密度值明显低于对照组,并随着年龄增长所呈现的骨密度下降发生率高于对照组,差异有统计学意义(P<0.01)。4在性别分组中发现,实验组女性T值均明显低于对照组,差异有统计学意义(P<0.05);且60岁以后尤其明显。5实验组中骨密度正常的27例患者中听力正常19例(70.37%),听力下降8例(29.63%);61例骨密度下降者中听力正常48例(78.69%),听力下降13例(21.31%)。听力损失与骨密度下降间的差异无统计学意义(P>0.05)。6Logistic回归结果提示骨密度高T值是BPPV的保护因素,OR=0.686(P<0.01,CI:1.32~5.85)。结论:BPPV患者骨密度值低于正常对照组,骨密度下降发生率较高,同时随年龄增加呈上升趋势,女性尤其明显。

Objective： Analyze BPPV in patients with ultrasonic bone mineral density to investigate the rela- tionship between the BPPV and bone density. Method..A total of 88 included subjects were selected from patients admitted to the Otolaryngological Department of Renhe Hospital, Beijing. Meanwhile, 76 healthy persons were included as control. The control group had similar age and gender distributions to the test group, and all healthy subjects had no history of vertigo in recent one year. Both groups underwent regular otolaryngological examina- tions, videonystagmography（VNG）, ultrasound bone densitometer test. According to gender, age, listening to group. Result.. （DBone density of the test group was significantly lower than the control group（- 2. 0104-1. 658 vs 0. 3605---4-_0. 875）, the difference was statistically significant（P^0.01） ;（~）Incidence rates of bone mass loss（35 in 88, 39.77~）and osteoporosis（26 in 88, 29.55%）bone mineral density decreased incidence of 69.32%, in the test group was significantly higher than that in the control group（bone mass loss, 13 in 76, 17.10% osteoporosis 6 in 76,7.89 %）, bone mineral density decreased incidence of 25.00%, the difference was statistically significant（P〈 0.01） ;（2）The test group and control group according to different age groups, the test group all ages bone density T values significantly lower than the control group（P〈0.01）, the difference was statistically significant. In the age groups, the incidence of bone loss was higher in the test group than that in the control group, the difference was statistically significant（P〈0.01）. （4）In the gender group, bone density of the test group women were signifi- cantly lower than the control group, the difference was statistically significant（P〈0.05） ; especially after the age of 60. （5）In the test group, 27 cases of bone mineral density is normal, with normal hearing 19 cases （70. 37%）, hearing loss 8 cases（29. 63%）;61 cases of bone loss, including normal hearing 48 cases （78.69 %）, hearing loss 13 cases （21.31% ）. The difference between hearing loss and bone loss had no statistical significance（P〉0.05）. （6）The logistic regression results showed that the prompt Higher bone mineral density T value was BPPV protection factors,OR= 0. 686, （P〈0.01,95% CI： 1.32--5.85）. Conclusion： BPPV in patients with bone mineral densi ty value is lower than the normal control group, there is a higher incidence of bone loss, at the same time, along with the age increasing on the rise, especially women.