Rh(D)阴性患者紧急抢救输血中应用“配合型输血”的回顾性分析

The Retrospective Analysis of Rh(D) Negative Patients with Special Circumstances of Emergency Rescue Transfusion Application of "Matching Blood Transfusion"

目的：回顾性分析Rh（D）阴性患者特殊情况紧急抢救输血应用“配合型输血”的病例资料，探讨应用配合型输血的安全性和有效性。方法对新疆阿克苏地区2014年1月-2015年12月Rh（D）阴性患者特殊情况紧急抢救输血6例应用“配合型输血”（病例组）及6例应用同型输血（对照组）的基本资料、红细胞抗体筛查、胆红素、血红蛋白（Hb）、网织红细胞计数（Ret）、红细胞比容（Hct）及住院天数（d）等进行统计分析，探讨配合型输血安全性与有效性。结果病例组与对照组输血后72 h红细胞抗体筛查阴性均未产生抗-D、输血后24 h Hb实际升高值分别为（28.53±10.09）g/L和（21.24±3.13）g/L、无非传染性输血并发症发生，病例组与对照组输血前后各指标的差异无统计学意义。结论 Rh（D）阴性患者特殊情况紧急抢救输血应用“配合型输血”是一种安全有效的临床输血治疗途径，同时对输注Rh（D）阳性红细胞的患者也应建立的规范的追踪、随访及评价体系。

Objective By the retrospective analysis of Rh（D） negative patients with special circumstances of emergency rescue transfusion application of ＂matching blood transfusion＂ case data,to explore the application of the safety and effectiveness of combined transfusion.Method Compared the effectiveness of6 matched blood transfusion（casegroup） and6 with same type blood transfusion（control group）in Xinjiang＇ aksu area from January2014 to December 2015,to explore matched blood transfusion＇s safety and effectiveness. The effectiveness indexes include patients basic information,red cell antibody screening,total bilirubin（TBIL）,concentration of hemoglobin（Hb）,reticulocyte count（Ret）,hematocrit（Hct）and hospitalization days.Results The patients in cases group and control group after blood transfusion72 h red cell antibody screening was negative and did not produce anti-D,Hb after blood transfusion24 h was actually appreciated in28.53±10.09 g/L and21.24±3.13 g/L,there was no significant difference compared with the experimental data of control group and case group by T text.Conclusion The matched blood transfusion of Rh（D）-negative matched blood transfusion with special circumstances of emergency rescue transfusion have the same effectiveness and safety,at the same time,the matched blood transfusion of the Rh（D）positive red blood cells of patients should also be established to standardize the trace,follow-up and evaluation system.