摘要
大黄攻邪力强,临床常用于热积腑实、血热出血、瘀血证及多种实热、湿热病证。本文结合本草文献及临床应用举例,介绍大黄在泻下与止泻、止血与活血、伤中与健胃3方面的双向调节作用;并查阅近10年的文献报道,综述大黄的化学成分及药理研究进展,分析总结上述双向调节作用的机理主要与大黄本身含有的多种化学成份而产生的药理多效性有关,为指导大黄的临床应用提供依据。
Rhubarb is good at attacking pathogenic factors,which is often applied on heat accumulation and fu- organ syndrome,blood-heat bleeding,blood stasis symptom and other sthenic heat and damp heat syndrome. This thesis introduces the two-way adjusting effects of rhubard on purgation and diarrhea,hemostasis and activating blood ,qi of middle-jiao energy harm and invigorating stomach based on literature on materia medica and clinical application instances. It also states the chemical composition of rhubarb and its pharmacological study develop- ment, analyzes the relation between the mechanism of the two-way adjusting effects of rhubard and the pharmacological pleiotropic effect generated by the multiple chemical composition in rhubarb on the basis of the literature reports for the recent 10 years, thus providing basis and support for the clinical application of rhubard.
出处
《中国中医急症》
2016年第12期2290-2291,2311,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
北京市属高等学校高层次人才引进与培养计划项目(CIT&TCD201504097)
首都医科大学校长基金教改课题(2015JYY43)
首都医科大学2015年第二课堂项目(D2KT2015)
中华医学会医学教育分会和中国高等教育学会医学教育专业委员会2016年医学教育研究立项课题(2016B-ZY002)
关键词
大黄
双向调节
化学成分
药理作用
Rhubard
Two,way adjusting effects
Chemical composition
pharmacological effect
