远程缺血预适应在缺血性脑血管疾病患者脑氧代谢及脑血流指标的影响

Study on the influence of remote ischemic preconditioning for the cerebral oxygen Metabolism and cerebral blood flow indexes of patients with ischemic cerebrovascular disease

目的:研究远程缺血预适应在缺血性脑血管疾病患者脑氧代谢及脑血流指标的影响。方法:选取于本院接受治疗的58例缺血性脑血管疾病患者为研究对象,随机分为观察组和对照组各29例,对照组进行常规治疗,观察组则在对照组的基础上加用远程缺血预适应训练,然后将两组治疗前和治疗后1个月、3个月与6个月时的脑氧代谢及脑血流指标进行分别检测与比较。结果:治疗前两组脑氧代谢及脑血流指标比较,差异均无统计学意义(P>0.05);而治疗后1个月、3个月与6个月时观察组的脑氧代谢及脑血流指标均优于本组治疗前及同时间的对照组,差异均具有统计学意义(P<0.05)。结论:远程缺血预适应在缺血性脑血管疾病患者脑氧代谢及脑血流指标的影响较好,对于缺血性脑血管疾病患者的应用价值较高。

Objective： To study and analyze the influence situation of remote ischemic preconditioning for the cerebral oxygen metabolism and cerebral blood flow indexes of patients with ischemic cerebrovascutar disease. Methods.. A total of 58 patients with ischemic cerebrovascular disease in our hospital were randomly divided into two groups, 29 patients in control group were treated with routine treatment,29 patients in observation group were treated with remote ischemic preconditioning on the basic treatment of control group, then the cerebral oxygen metabolism and cerebral blood flow indexes of two groups be- fore the treatment and at first, third and sixth month after the treatment were respectly detected and compared. Results： The cerebral oxygen metabolism and cerebral blood flow indexes of two groups before the treatment all had no significant differ- ences, （P all〉0.05）, while the cerebral oxygen metabolism and cerebral blood flow indexes of observation group at first, third and sixth month after the treatment were all significantly better than those before the treatment, and the results were all better than those of control group at the same time too, all P〈0.05, the differences were all significant. Conclusion：The influence of remote isehemic preconditioning for the cerebral oxygen metabolism and cerebral blood flow indexes of patients with ischemic cerebrovascular disease are better, and its application value for the patients with ischemic cerebrovascular disease is higher.