益气活血法治疗冠心病气虚血瘀证的用药规律分析

Analysis of Medication Rules of Corrective Treatment for Coronary Heart Disease of Qi- deficiency and Blood- stasis Syndrome

目的挖掘益气活血法治疗气虚血瘀型冠心病的频次和特征,为该类患者的治疗提供参考。方法利用计算机检索中国期刊全文数据库(CNKI),将符合标准的文献中的数据进行药的频次、主治的统计,并总结用药规律及特征。结果检索到符合标准的文献48篇,经过统计用药频次前3位的益气药的分别是黄芪、党参、人参。使用频次在前5位的活血化瘀药有丹参、川芎、红花、桃仁、郁金。结论利用文本挖掘的方法,可以从冠心病气虚血瘀证临床试验文献中探索中医诊疗规律,为临床辨证用药及研究的深入开展提供参考依据。

Objective The aim of this investigate is to study and reveal the clinical medication regulation of coronary heart disease （CHD） qi - deficiency and blood - stasis syndrome. Methods We used ＂CHD＂ and ＂qi - deficiency and blood - stasis＂ as keywords to search medical journal in China Academic Journal Database （CNKI） , collect the data meeting the requirements, and analyse the frequence of eommomly used traditional Chinese medicine（TCM） ,the classification of commomly used TCM, characteristics of medication. Results A total of 48 qualified literatures were referred,involving 68 related drugs. The commomly used TCM, by frequency from high to low, as fol- lows ： Radix astragalix, Radix Salviae Mihiorrhizae, Rhizoma chuanxiong, Honghua, Radix Angelicae Sinensis, Radix notoginseng, Codonop- sis pliosula,Radix Paeoniae Rubra, ginseng. From the function aspect, qi - supplementing and blood - activating herbs, qi - regulating herbs,dampness resolving herbs were indentified as high frequency medicines. Conclusion Data mining is able to explore the medication rule of CHD qi - deficiency and blood - stasis syndrome , which be able to guide the clinic and TCM development.