摘要
微小RNA(miRNA)是一类长度约为22nt的小分子非编码单链RNA,其功能主要是在转录后水平对基因表达进行调节,从而参与众多生命活动的调控。无核的血小板在止血和凝血过程中起着重要的作用,深入了解miRNA在血小板生成和活化中的作用,将为血小板相关的血液系统性疾病的治疗提供了新的思路。
MicroRNA(miRNA) is 22-nucleotide noncoding single-stranded RNA. Its main function is to regulate gene expression after transcription,so as to participate in regulating biologic activity. Though platelet has no cell nucleus,it plays an important role in hemostasis and coagulation processes. Understanding the role of platelet production and activity deeply will provide new ideas for the treatment of platelet-related blood systemic diseases.
出处
《检验医学》
CAS
2016年第11期997-1001,共5页
Laboratory Medicine
关键词
血小板
生成
活化
Platelet
MicroRNAs
Generation
Activation