移居高原汉族人群返回平原初红细胞与血脂指标的相关性分析

Analysis on correlation between RBC and blood lipid indexes in early returning to plain of Han high altitude immigration

目的探讨平原移居人群在高原习服过程中出现红细胞(RBC)和血脂的变化及其相关性。方法选择进入西藏阿里地区工作1年的汉族男性教师40例,分别于进入高原前和返回平原后3d内采血,检测血常规和血脂水平。结果返回平原初,研究对象的RBC、三酰甘油(TG)、总胆固醇(CHO)、低密度脂蛋白胆固醇(LDL-C)水平升高,其中RBC、TG有显著升高(P<0.01),高密度脂蛋白胆固醇(HDL-C)显著降低(P<0.01);返回平原后,RBC与TG、CHO呈正相关(分别为r=0.46,P<0.01和r=0.36,P<0.05)。结论高原低氧环境是导致平原人群进入高原环境后RBC和血脂指标改变的根本原因。

Objective To investigate the changes of red blood cells（RBC）and blood lipid in Han high altitude immigration during the process of altitude acclimatization and their correlation.Methods Forty male Han nationality teachers entering Xizang Ali area and working for 1year were selected.The blood samples were collected before entering plateau and within 3dafter returning to plain.The blood routine and the blood lipid level were detected.Results In the early return to plain,the RBC,TG,CHO and LDL-C levels in the research subjects were increased,in which RBC and TG were significantly increased（P〈0.01）,HDL-C was significantly decreased.After returning to plain,RBC was positively correlated with TG and CHO（r=0.46,P〈0.01 and r=0.36,P〈0.05）.Conclusion High altitude hypoxia environment is the primary cause leading to the change of RBC and blood lipid indexes in the plain population after entering the plateau environment.